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	<title>Comments on: Daily (intermittent) Open-Ended Puzzle: Skull-brain evolution</title>
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	<link>http://www.hyperorg.com/blogger/2009/05/28/daily-intermittent-open-ended-puzzle-skull-brain-evolution/</link>
	<description>Let's just see what happens</description>
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		<title>By: Greg Lloyd</title>
		<link>http://www.hyperorg.com/blogger/2009/05/28/daily-intermittent-open-ended-puzzle-skull-brain-evolution/comment-page-1/#comment-47417</link>
		<dc:creator>Greg Lloyd</dc:creator>
		<pubDate>Fri, 29 May 2009 17:05:03 +0000</pubDate>
		<guid isPermaLink="false">http://www.hyperorg.com/blogger/2009/05/28/daily-intermittent-open-ended-puzzle-skull-brain-evolution/#comment-47417</guid>
		<description><![CDATA[I don&#039;t know the answer to your evolutionary question. Aside from that I have a hard time getting around the deeply disturbing implications of more intelligent and persistent squirrel kind.]]></description>
		<content:encoded><![CDATA[<p>I don&#8217;t know the answer to your evolutionary question. Aside from that I have a hard time getting around the deeply disturbing implications of more intelligent and persistent squirrel kind.</p>
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		<title>By: James</title>
		<link>http://www.hyperorg.com/blogger/2009/05/28/daily-intermittent-open-ended-puzzle-skull-brain-evolution/comment-page-1/#comment-47415</link>
		<dc:creator>James</dc:creator>
		<pubDate>Fri, 29 May 2009 16:02:01 +0000</pubDate>
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		<description><![CDATA[It&#039;s been a while since I read &quot;The Plausibility of Life&quot; but I recall that Kirschner et al describe how the growth signaling of fetal structures are interelated so that yes, a change/mutation in one area (eg, skeletal structure) will trigger appropriate changes in the formation of muscle, vascular structure, skin, etc. My foggy layman&#039;s description - not so much controlled by the same gene, but some systems use (I&#039;ll call it) second-order signaling to conform to the fundamental genetic signals. So no, you don&#039;t necessarily need multiple, coordinated changes in genes to trigger useful mutations.]]></description>
		<content:encoded><![CDATA[<p>It&#8217;s been a while since I read &#8220;The Plausibility of Life&#8221; but I recall that Kirschner et al describe how the growth signaling of fetal structures are interelated so that yes, a change/mutation in one area (eg, skeletal structure) will trigger appropriate changes in the formation of muscle, vascular structure, skin, etc. My foggy layman&#8217;s description &#8211; not so much controlled by the same gene, but some systems use (I&#8217;ll call it) second-order signaling to conform to the fundamental genetic signals. So no, you don&#8217;t necessarily need multiple, coordinated changes in genes to trigger useful mutations.</p>
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		<title>By: Andy Weinberger (yes, I am related)</title>
		<link>http://www.hyperorg.com/blogger/2009/05/28/daily-intermittent-open-ended-puzzle-skull-brain-evolution/comment-page-1/#comment-47403</link>
		<dc:creator>Andy Weinberger (yes, I am related)</dc:creator>
		<pubDate>Fri, 29 May 2009 03:02:19 +0000</pubDate>
		<guid isPermaLink="false">http://www.hyperorg.com/blogger/2009/05/28/daily-intermittent-open-ended-puzzle-skull-brain-evolution/#comment-47403</guid>
		<description><![CDATA[With respect to evolution, I have no direct answer.  Actually, it would be easier if I didn&#039;t believe in evolution.  But, non-evolutionarily (?), in infancy if the head contents enlarge, as in hydrocephaly, the skull enlarges to contain it, at least until the skull &quot;joints&quot; grow together in ossification.]]></description>
		<content:encoded><![CDATA[<p>With respect to evolution, I have no direct answer.  Actually, it would be easier if I didn&#8217;t believe in evolution.  But, non-evolutionarily (?), in infancy if the head contents enlarge, as in hydrocephaly, the skull enlarges to contain it, at least until the skull &#8220;joints&#8221; grow together in ossification.</p>
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